Research design and methods: seeral methods were used to modulate cholesterol leels in intact islets and cultured?-cells, including a recently deeloped mouse model that exhibits eleated cholesterol but normal free fatty acid leels. 实验设计和方法:在完整的胰岛及培养的?-细胞中,已有很多方法用于调节胆固醇水平,包括最近兴起的一种大鼠模型,其胆固醇水平增高,但自由脂肪酸正常。
When administered orally with STT for 14 days, both normal and type 2 diabetic rats showed a significantly lowered serum triglyceride and cholesterol, and the diabetic rats also had a markedly decreased levels of free fatty acid. 在蒺藜皂苷处理14d后,正常和2型糖尿病大鼠的血清甘油三酯和血清胆固醇的含量都显著下降,而在2型糖尿病大鼠中,游离脂肪酸的含量也显著降低。